Wednesday, August 04, 2010

Paternal age increases the risk for autism in an Iranian population sample.

http://www.ncbi.nlm.nih.gov/pubmed/20678245

Mol Autism. 2010 Feb 22;1(1):2.

Paternal age increases the risk for autism in an Iranian population sample.
Sasanfar R, Haddad SA, Tolouei A, Ghadami M, Yu D, Santangelo SL.

Department of Psychiatry, Harvard Medical School, Boston, MA, USA. ssantangelo@pngu.mgh.harvard.edu.

Abstract
ABSTRACT: BACKGROUND: Autism is a neurodevelopmental disorder which is known to have a strong genetic component and is most likely oligogenic. However, the necessary role of environmental factors has been well documented. Prior research suggests that parental characteristics, such as age and level of education, may be associated with a risk of autism. Parental age has been shown to be associated with many disorders, such as schizophrenia, childhood cancer and fetal death. However, results from studies of parental age and autism are inconsistent. METHODS: In the present study, we investigated the association of autism with parental age in 179 autism cases and 1611 matched cohort children from Iran. Each case was matched with nine cohort controls on parental education, sex, order of birth, consanguineous marriage, urbanism and province of residence. The Cox regression model was used to carry out conditional logistic regression on the matched data. RESULTS: There was a significant association between higher paternal age, but not maternal age, and an increasing risk of autism. An analysis of the combined effect of parental age and education also revealed that parents with higher education had an increased risk of having autistic children, with a dose-response effect of parental age. CONCLUSIONS: This study, which is

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6 Comments:

At 11:20 AM, Blogger 凱v胡倫 said...

河水永遠是相同的,可是每一剎那又都是新的。............................................................

 
At 3:13 AM, Blogger 罗韬 said...

所有的資產,在不被諒解時,都成了負債..................................................................

 
At 5:30 PM, Blogger 446 said...

所有的資產,在不被諒解時,都成了負債..................................................................

 
At 12:16 AM, Blogger 建曹宏建曹宏 said...

不要去想沒拿到的東西,多想想自己手裡所擁有的..................................................

 
At 12:41 AM, Blogger 靜錢錢錢怡錢錢錢錢 said...

所有的資產,在不被諒解時,都成了負債............................................................

 
At 7:44 AM, Blogger 8468 said...

看到大家都留言-我也忍不住說聲---加油..................................................

 

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